A Research Associate I position is available starting May 1 2012. For details see:

http://jobs.bidmc.org/boston/research/jobid2129219-research-assistant-i-jobs

Positions Available
Archived News 2011 (cont.) Maria Mancini has left the lab to take a position at Biomodels. Best of luck Maria! Aura Kaunisto attended the Gordon Research Conference on Angiogenesis, and presented a poster. She was awarded a travel scholarship from the Magnus Ehrnrooth Foundation to attend the meeting. Rebecca Chin has been awarded a K99 Howard Temin Pathway to Independence Award from the National Cancer Institute. Congratulations Rebecca! Claudine Cohick has left the lab and joined the laboratory of Dr. Levi Garraway at The Broad Institute in Boston for her post-doc. Best of luck Claudine!! Alex Toker presented a seminar in the Department of Biochemistry and Molecular Biology at the LSU Health Sciences Center May 5 2011. The lab welcomes Whitney Henry, G1 student in the BBS Program at HMS, who is joining the lab for her thesis project. Welcome Whitney! Review published! Chin, R. Y and Toker, A. Akt isoform-specific signaling in breast cancer: Uncovering an anti-migratory role for palladin. Cell Adhesion and Migration, 2011: May 1;5(3) Emilie Collmann has been awarded a 2011 Susan G. Komen for the Cure Postdoctoral fellowship! Congratulations Emilie! Alex Toker presented a seminar in the Blaffer Seminar Series at M.D. Anderson Cancer Center, Houston, on March 29 2011. Alex Toker presented a seminar at the Cancer Research UK London Research Institute on March 24 2011. Alex Toker presented a seminar in the Department of Biochemistry and Molecular Biology at the University of Kentucky on March 2 2011. The lab attended the Keystone Symposia on PI 3-Kinase Signaling Pathways in Keystone, February 13-18, 2011. Alex presented a talk and Maria, Sivan, Emilie Jessica and Kristin presented posters. Jessica was awarded a travel scholarship to attend the meeting! Photos of the meeting here. Alex attended the CNIO Frontiers Breast Cancer symposium in Madrid, February 7-9, 2011. The lab welcomes Karina Gonzalez, G1 student in the BBS PhD program, for her second lab rotation! The lab welcomes Dr. Colin White, new post-doctoral fellow. Colin received his PhD from the University of Edinburgh, Scotland, and was a post-doctoral fellow in the laboratory of Dr. David Sacks at Brigham and Women’s Hospital, HMS, 2008-2010. His research if funded by a DoD Breast Cancer Research Program fellowship. Welcome Colin! Claudine Cohick defended her PhD Thesis in the Division of Medical Sciences at Harvard Medical School on Friday January 14th, 2011. The title of her thesis is “Protein Kinase D Signaling Through Substrate Phosphorylation in Endocytic Trafficking”. Congratulations Dr. Cohick!! Photos of the great day here. 2010 Kristin Brown has been awarded a 2010 John Gavin Postdoctoral Fellowship from the Genesis Oncology Trust of New Zealand! Congratulations Kristin! November 2010: Alex Toker is promoted to Full Professor of Pathology at Harvard Medical School! Magnificent celebrations to follow. Aura Kaunisto has been awarded a 2010 Orion-Farmos Research Foundation fellowship! Congratulations Aura! Paper published! Chin, R. Y and Toker, A. Akt2 regulates Expression of the Actin-Bundling Protein Palladin. FEBS Letters 2010, doi:10.1016/j.febslet.2010.10.056 Aura Kaunisto has been awarded a 2010 Oskari Huttunen Foundation fellowship! Congratulations Aura! The Toker lab welcomes new post-doctoral fellow Dr. Aura Kaunisto, who recently received her PhD from the University of Turku and the Turku Graduate School of Biomedical Sciences in Finland in the laboratory of John E. Eriksson. Welcome Aura! The Toker lab bids farewell to Amy Carr, lab manager and Research Assistant since 2007. Best of luck to Amy at MGH! Paper published! Fry, J. S. and Toker, A. Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration. Cancer Research 2010, 70(20): 8187-8198 The lab welcomes Heather Gardiner, new Research Assistant and Toker lab manager. Welcome Heather! The lab welcomes Whitney Henry, G1 student in the BBS PhD program, for her first lab rotation! Paper published! Chin, Y. R. and Toker, A. The actin bundling protein Palladin is an Akt1-specific substrate that regulates breast cancer cell migration. Molecular Cell 2010, 38 (3) 333-344. Read all about it in the BIDMC press release and video interview with the lab! Evaluated on Faculty of 1000 Paper published! Nhek, S., Ngo, M., Yang, X., Ng, M., Field, S. J., Asara, J. M., Ridgeway, N. D. and Toker, A. Regulation of OSBP Golgi Localization Through Protein Kinase D-mediated Phosphorylation. Molecular Biology of the Cell 2010, 21: 2327-2337. Rebecca Chin has been awarded an AACR-Women in Cancer Research Scholar Award! Congratulations Rebecca! Photos of the AACR WICR reception with Rebecca, other awardees along with 2010 Nobel Laureate Dr. Elizabeth Blackburn. Alex Toker, Sivan Elloul, Rebecca Chin and Maria Mancini attended the 101st Annual AACR (American Association for Cancer Research) Meeting in Washington, DC, April 17-21, 2010. Alex co-chaired the Cancer Signaling mini-symposium, and Rebecca’s abstract was selected for an oral presentation, congratulations Rebecca! Photos here. Sivan Elloul has been awarded a Department of Defense 2010 Breast Cancer Research Program Post-doctoral fellowship! Congratulations Sivan! Alex Toker attended the Cold Spring Harbor Laboratory on PTEN Pathways and Targets, March 16-20, 2010. Some photos here The Toker lab welcomes two new post-doctoral fellows. Dr. Emilie Collmann, who recently received her PhD from the University of Basel, Switzerland, in the laboratory of Matthias Wymann. Dr. Kristin Brown, who received her PhD from the University of Otago, Christchurch, New Zealand, in the laboratory of Christine Winterbourn. Welcome!! Sokha Nhek has left the lab and joined ImClone Inc. in New York City for her post-doc. She is working in the laboratory of Dr. Laura Benjamin. Best of luck Sokha!! 2009 Jessica Fry has left the lab and joined the laboratory of Dr. Richard Cohen at Boston University School of Medicine for her post-doc. Best of luck Jessica!! Preview Published! TTC3 Ubiquitination Terminates Akt-ivation. Toker A. Developmental Cell 2009: 17, 752-754 Alex Toker presented a seminar at the Institute of Cancer at Barts and the London School of Medicine and Dentistry, London, UK, on December 8 2009. Jessica Fry defended her PhD Thesis in the HMS Biological and Biomedical Sciences graduate program on November 19, 2009. The title of her Dissertation was ‘ADAM9 Metalloproteases and Breast Cancer Cell Migration’. Congratulations Dr. Jessica Fry!! Photos here. Alex Toker presented a seminar at IRIC, Institut de Recherche en Immunologie et en Cancérologie, University of Montreal, Canada, on November 16 2009. Alex Toker presented a seminar in the Department of Biochemistry and Molecular Biology at the Oregon Health & Science University in Portland, Oregon on November 10 2009. Review Published! NFAT Proteins: Emerging Roles in Cancer Progression. Mancini, M. and Toker A. Nature Reviews Cancer 2009: 9, 810-820. Alex Toker presented a seminar at the University of Arizona Cancer Center in Tucson on October 26 2009. Alex Toker attended the workshop on Phospholipid Signaling and Transport, in memory of the late Prof. Moti Liscovitch, at the Weizmann Institute of Science in Rehovot, Israel, October 15, 2009. Photos here. Jessica Gasser was awarded a Department of Defense 2009 Breast Cancer Research Program Pre-doctoral fellowship! Congratulations Jess! Jessica Fry and Maria Mancini attended the AACR focused meeting on Frontiers in Basic Cancer Research in Boston, October 8-11, 2009. Jessica gave a poster presentation. Sokha Nhek defended her PhD Thesis in the HMS Biological and Biomedical Sciences graduate program on September 11, 2009. The title of her Dissertation was ‘Protein Kinase D Signaling Through Substrate Phosphorylation’. Congratulations Dr. Sokha Nhek!! Photos here. Paper published! Storz, P., Döppler, H., Copland, J. A., Simpson, K. J. and Toker, A. The FOXO3a Transcription Factor Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases. Molecular and Cellular Biology 2009, 29 (18): 4906-4917. Alex Toker attended the FASEB Summer Research Conference on Lipid Signaling Pathways in Cancer at the Carefree Resort, Carefree, AZ, July 19-24, 2009. Sokha Nhek attended the FASEB Summer Research Conference on Protein Kinases and Protein Phosphorylation in Snowmass Village, CO, July 26-31, 2009. Sokha presented a poster on her thesis work. Alex Toker gave the annual Paul M. Horowitz Memorial lecture in the Department of Biochemistry at the University of Texas Health Science Center at San Antonio on May 15 2009. Photos here. Alex Toker, Jessica Fry and Maria Mancini attended the Annual FASEB/Experimental Biology meeting in New Orleans, LA, April 18-22 2009. Alex was the co-organizer for the Principles of Receptor Signaling Theme for the ASBMB Annual Symposium. Jessica Fry was awarded an ASBMB Poster Prize, congratulations Jessica! Rebecca Chin attended the Annual AACR (American Association for Cancer Research) Meeting in Denver, CO, April 18-22. Rebecca’s poster was selected for an oral presentation, congratulations Rebecca! Alex Toker attended the Gordon Conference on Insulin-Like Growth Factors in Physiology and Disease in Ventura, CA, March 22-27 2009. Paper published! Akt/Protein Kinase B and Glycogen Synthase Kinase-3{beta} Signaling Pathway Regulates Cell Migration through the NFAT1 Transcription Factor. Yoeli-Lerner M, Chin YR, Hansen CK, Toker A. Mol Cancer Res. 2009 Paper published! Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Nat Cell Biol. 2009. Review Published! Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer. Chin YR, Toker A. Cell Signal. 2009 Apr;21(4):470-6 The lab attended the annual Dana-Farber/Harvard Cancer Center Breast Cancer Program retreat at the Harvard Club on March 6, 2009. Rebecca Chin and Jessica Fry gave poster presentations. 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