Alex Toker received a BSc from King's College, University of London, UK in 1987 and a PhD from the National Institute for Medical Research, London, UK in 1991. He conducted his post-doctoral research in the laboratory of Prof. Lewis Cantley, first in the Department of Physiology, Tufts University School of Medicine, then in the Department of Cell Biology, Harvard Medical School and Division of Signal Transduction, Beth Israel Deaconess Medical Center. His first faculty appointment was as Staff Scientist at the Boston Biomedical Research Institute in 1997, where he was promoted to Principal Scientist in 1999. In 2000 he joined the faculty of Beth Israel Deaconess Medical Center and Harvard Medical School as an Assistant Professor in the Department of Pathology. In 2003, he was promoted to Associate Professor and joined the faculty of the HMS PhD program in Biological and Biomedical Sciences.


Other Activities:

  1.   Vice Chair, Reviews, The Biochemical Journal

  2.   Editorial Board, Molecular and Cellular Biology 

  3.   Member of Faculty of 1000

  4.   Chair, Editorial Advisory Board, ASBMB Today


Alex Toker, PhD

Post-docs

Rebecca Chin, PhD

Sivan Elloul, PhD

Maria Mancini, PhD

Jessica Gasser

Graduate Students

Claudine Christoforides

Research Assistants

Emilie Collmann, PhD

Rebecca Chin Received her PhD from Albert Einstein College of Medicine. Her research focuses on the molecular mechanisms by which PI 3-K and Akt signaling promotes breast cancer invasion and metastasis. She is a recipient of a 2007 Susan G. Komen Breast Cancer Foundation award. In addition, Rebecca is a recipient of a Scholar-in-Training Award from the AACR and Aflac, Inc. (2009), and a recipient of an AACR Women in Cancer Research Award (2010). In December 2009, Rebecca was promoted to Instructor in Pathology at Harvard Medical School.

Maria Mancini received her PhD from the University of Maine at the Maine Medical Center Research Institute. Her research focuses on the molecular mechanisms by which Akt and NFAT signaling regulates breast cancer progression. She is a recipient of a 2008 NIH F32 Fellowship Training award.

Sivan Elloul received her PhD from the Hebrew University of Jerusalem. Her current research focuses on the Akt pathway and cell survival. She is a recipient of a 2010 DOD Breast Cancer Research Program post-doctoral fellowship award.

Jessica Gasser received her BS degree from the University of Illinois, Urbana/Champaign. Her research focuses on the PI 3-K and SGK pathway in the regulation of breast cancer progression. She is a recipient of a 2010 DOD Breast Cancer Research Program pre-doctoral fellowship award.

Claudine Christoforides received her BA degree from St. John’s College. Her research focuses on the PKD signaling pathway and how it impacts cancer cell signaling. She is a recipient of a 2006 DOD Breast Cancer Research Program pre-doctoral fellowship award.

Emilie Collmann received her BS degree from Henri Poincare University, Nancy, France, and her PhD from the University of Basel, Switzerland in the laboratory of Matthias Wymann. Her research focuses on the PI 3-K signaling pathway in cancer.

Former Lab Members

Sebastien Jauliac (lab link)

Peter Storz (lab link)

Merav Yoeli-Lerner

Antonio Mazzocca

Gary Yiu

Vittoria Cenni

Alessandra Sirri

Lauren Harkins

Wendy Chaplis

Heike Doeppler

Maribeth Wert

Students

Post-Docs

Technicians

Sokha Nhek (PhD 2009)

Jessica Fry (PhD 2009)

Kristin Brown, PhD

Kristin Brown received her BS degree from the University of Canterbury, Christchurch, New Zealand, and her PhD from the University of Otago, Christchurch, New Zealand in the laboratory of Christine Winterbourn. Her research focuses on the Akt protein kinase and substrate specificity in breast cancer. 

Heather Gardiner

Heather Gardiner received her BS degree from Northeastern University. Heather is the new Toker lab manager!

Instructors

Aura Kaunisto, PhD

Aura Kaunisto received her PhD degree from the University of Turku and the Turku Graduate School of Biomedical Sciences in Finland in the laboratory of John E. Eriksson. Aura will be joining the Toker lab on September 1st, 2010.

Amy Carr